Camptocormia (bent spine) in patients with Parkinson's disease—Characterization and possible pathogenesis of an unusual phenomenon
Identifieur interne : 004D94 ( Main/Exploration ); précédent : 004D93; suivant : 004D95Camptocormia (bent spine) in patients with Parkinson's disease—Characterization and possible pathogenesis of an unusual phenomenon
Auteurs : Ruth Djaldetti [Israël] ; Ronit Mosberg-Galili [Israël] ; Haza Sroka [Israël] ; Doron Merims [Israël] ; Eldad Melamed [Israël]Source :
- Movement Disorders [ 0885-3185 ] ; 1999-05.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Personne âgée.
English descriptors
- KwdEn :
- Aged, Antineoplastic Agents (therapeutic use), Bending, Bent spine, Brain (pathology), Brain (radiography), Camptocormia, Diagnosis, Dorsolumbar spine, Elderly, Electromyography (methods), Female, Humans, Idiopathic, Levodopa (therapeutic use), Magnetic Resonance Imaging, Male, Middle Aged, Parkinson Disease (complications), Parkinson Disease (drug therapy), Parkinson disease, Parkinson's disease, Pathogenesis, Posture, Severity of Illness Index, Spinal Diseases (diagnosis), Spinal Diseases (drug therapy), Spinal Diseases (etiology), Symptomatology, Tilt, Tomography, X-Ray Computed.
- MESH :
- chemical , therapeutic use : Antineoplastic Agents, Levodopa.
- complications : Parkinson Disease.
- diagnosis : Spinal Diseases.
- drug therapy : Parkinson Disease, Spinal Diseases.
- etiology : Spinal Diseases.
- methods : Electromyography.
- pathology : Brain.
- radiography : Brain.
- Aged, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Posture, Severity of Illness Index, Tomography, X-Ray Computed.
Abstract
Camptocormia is characterized by severe forward flexion of the thoracolumbar spine which increases while walking and disappears in the recumbent position. We describe for the first time eight patients with presumed idiopathic Parkinson's disease (mean age 66 ± 5 yrs; mean symptom duration 13.1 ± 5.1 yrs) who developed camptocormia. This impressive abnormal posture emerged 4–14 years from disease onset, and in some patients stooped posture was the prominent symptom at diagnosis. There was no clear correlation between camptocormia and levodopa treatment. In some patients the camptocormic posture improved, and in others it was unchanged or even aggravated following levodopa administration. Three patients reported worsening of this symptom during “off” periods and also with fatigue. The pathogenesis of this phenomenon is unknown but might represent either a rare type of dystonia or an extreme form of rigidity.
Url:
DOI: 10.1002/1531-8257(199905)14:3<443::AID-MDS1009>3.0.CO;2-G
Affiliations:
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Le document en format XML
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first="Ruth" last="Djaldetti">Ruth Djaldetti</name><affiliation wicri:level="1"><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Neurology, Rabin Medical Center, Beilinson Campus, Petah Tiqva, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv</wicri:regionArea><wicri:noRegion>Tel Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Mosberg Alili, Ronit" sort="Mosberg Alili, Ronit" uniqKey="Mosberg Alili R" first="Ronit" last="Mosberg-Galili">Ronit Mosberg-Galili</name><affiliation wicri:level="1"><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Neurology, Rabin Medical Center, Beilinson Campus, Petah Tiqva, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv</wicri:regionArea><wicri:noRegion>Tel Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Sroka, Haza" sort="Sroka, Haza" uniqKey="Sroka H" first="Haza" last="Sroka">Haza Sroka</name><affiliation wicri:level="1"><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Neurology, Rabin Medical Center, Beilinson Campus, Petah Tiqva, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv</wicri:regionArea><wicri:noRegion>Tel Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Merims, Doron" sort="Merims, Doron" uniqKey="Merims D" first="Doron" last="Merims">Doron Merims</name><affiliation wicri:level="1"><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Neurology, Rabin Medical Center, Beilinson Campus, Petah Tiqva, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv</wicri:regionArea><wicri:noRegion>Tel Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Melamed, Eldad" sort="Melamed, Eldad" uniqKey="Melamed E" first="Eldad" last="Melamed">Eldad Melamed</name><affiliation wicri:level="1"><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Neurology, Rabin Medical Center, Beilinson Campus, Petah Tiqva, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv</wicri:regionArea><wicri:noRegion>Tel Aviv</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>John Wiley & Sons, Inc.</publisher><pubPlace>New York</pubPlace><date type="published" when="1999-05">1999-05</date><biblScope unit="vol">14</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="443">443</biblScope><biblScope unit="page" to="447">447</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">50900BD0E52C527AEE6E0E3FA92137129FBE3B26</idno><idno type="DOI">10.1002/1531-8257(199905)14:3<443::AID-MDS1009>3.0.CO;2-G</idno><idno type="ArticleID">MDS1009</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Antineoplastic Agents (therapeutic use)</term><term>Bending</term><term>Bent spine</term><term>Brain (pathology)</term><term>Brain (radiography)</term><term>Camptocormia</term><term>Diagnosis</term><term>Dorsolumbar spine</term><term>Elderly</term><term>Electromyography (methods)</term><term>Female</term><term>Humans</term><term>Idiopathic</term><term>Levodopa (therapeutic use)</term><term>Magnetic Resonance Imaging</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (complications)</term><term>Parkinson Disease (drug therapy)</term><term>Parkinson disease</term><term>Parkinson's disease</term><term>Pathogenesis</term><term>Posture</term><term>Severity of Illness Index</term><term>Spinal Diseases (diagnosis)</term><term>Spinal Diseases (drug therapy)</term><term>Spinal Diseases (etiology)</term><term>Symptomatology</term><term>Tilt</term><term>Tomography, X-Ray Computed</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antineoplastic Agents</term><term>Levodopa</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Spinal Diseases</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Parkinson Disease</term><term>Spinal Diseases</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Spinal Diseases</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Electromyography</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Brain</term></keywords><keywords scheme="MESH" qualifier="radiography" xml:lang="en"><term>Brain</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Female</term><term>Humans</term><term>Magnetic Resonance Imaging</term><term>Male</term><term>Middle Aged</term><term>Posture</term><term>Severity of Illness Index</term><term>Tomography, X-Ray Computed</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Camptocormia</term><term>Diagnostic</term><term>Flexion</term><term>Idiopathique</term><term>Inclinaison</term><term>Parkinson maladie</term><term>Pathogénie</term><term>Personne âgée</term><term>Posture</term><term>Rachis dorsolombaire</term><term>Symptomatologie</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Personne âgée</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Camptocormia is characterized by severe forward flexion of the thoracolumbar spine which increases while walking and disappears in the recumbent position. We describe for the first time eight patients with presumed idiopathic Parkinson's disease (mean age 66 ± 5 yrs; mean symptom duration 13.1 ± 5.1 yrs) who developed camptocormia. This impressive abnormal posture emerged 4–14 years from disease onset, and in some patients stooped posture was the prominent symptom at diagnosis. There was no clear correlation between camptocormia and levodopa treatment. In some patients the camptocormic posture improved, and in others it was unchanged or even aggravated following levodopa administration. Three patients reported worsening of this symptom during “off” periods and also with fatigue. The pathogenesis of this phenomenon is unknown but might represent either a rare type of dystonia or an extreme form of rigidity.</div></front></TEI><affiliations><list><country><li>Israël</li></country></list><tree><country name="Israël"><noRegion><name sortKey="Djaldetti, Ruth" sort="Djaldetti, Ruth" uniqKey="Djaldetti R" first="Ruth" last="Djaldetti">Ruth Djaldetti</name></noRegion><name sortKey="Melamed, Eldad" sort="Melamed, Eldad" uniqKey="Melamed E" first="Eldad" last="Melamed">Eldad Melamed</name><name sortKey="Merims, Doron" sort="Merims, Doron" uniqKey="Merims D" first="Doron" last="Merims">Doron Merims</name><name sortKey="Mosberg Alili, Ronit" sort="Mosberg Alili, Ronit" uniqKey="Mosberg Alili R" first="Ronit" last="Mosberg-Galili">Ronit Mosberg-Galili</name><name sortKey="Sroka, Haza" sort="Sroka, Haza" uniqKey="Sroka H" first="Haza" last="Sroka">Haza Sroka</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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